Intranasal insulin improves mitochondrial function and attenuates motor deficits in a rat 6-OHDA model of Parkinson's disease.

Farideh IravanpourLeila Dargahi Mohsen Rezaei Masoud Haghani Reza Heidari Neda Valian Abolhassan Ahmadiani

Published in: CNS neuroscience & therapeutics (2021)

Considering the prominent role of mitochondrial dysfunction in PD pathology, IN insulin as a disease-modifying therapy for PD should be considered for extensive research.

Keyphrases

type diabetes
glycemic control
traumatic brain injury
oxidative stress
metabolic syndrome