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Combined hereditary thrombophilias are responsible for poor placental vascularization development and low molecular weight heparins (LMWH) prevent adverse pregnancy outcomes in these patients.

Miroslava G GojnicStefan V DugalicAleksandar O StefanovicKatarina V StefanovicMilos A PetronijevicSvetlana M Vrzic PetronijevicIgor V PanticMilan D PerovicBrankica I VasiljevicNemanja M MilincicMilica M ZaricJovana S TodorovicMaja Macura
Published in: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians (2020)
Thrombophilias should be considered and screened when poor vascularization is noted early in the pregnancy with Doppler sonography. Intervention with LMWH prevents adverse PO in these patients.
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