Coronary Artery Plaque Composition and Severity Relate to the Inflammasome in People With Treated Human Immunodeficiency Virus.
Samuel R SchnittmanDouglas W KitchTalia H SwartzTricia H BurdoKathleen V FitchSara McCallumJacqueline M FlynnEvelynne S FuldaMarissa R DiggsJack T StapletonJosé L CasadoJana TaronJudith S CurrierMarkella V ZanniCarlos MalvestuttoCarl J FichtenbaumJudith A AbergHeather J RibaudoMichael T LuPamela S DouglasSteven K GrinspoonPublished in: Open forum infectious diseases (2023)
As Leaman score >5 is associated with cardiovascular events in the general population, future work is needed to determine how the inflammasome relates to events and whether strategies to reduce its activation affect events or plaque progression among PWH.