Duplications in 19p13.3 are associated with male infertility.

Vertika SinghRenu BalaArijit ChakrabortySingh RajenderSameer TrivediKiran Singh

Published in: Journal of assisted reproduction and genetics (2019)

The result clearly indicates the significance of 19p13.3 duplication in infertile men with severe testicular phenotypes. The present study underlines the utility and significance of whole genomic analysis in the cases of male infertility which goes undiagnosed due to limitations in the conventional cytogenetic techniques and for identifying genes that are essential for spermatogenesis.

Keyphrases

polycystic ovary syndrome
early onset
genome wide
gene expression
metabolic syndrome
bioinformatics analysis
transcription factor