Lack of rewarding effects of a soluble epoxide hydrolase inhibitor TPPU in mice: Comparison with morphine.

Xiayun WanYuko FujitaLijia ChangYan WeiLi MaGerile WuyunYaoyu PuBruce D HammockKenji Hashimoto

Published in: Neuropsychopharmacology reports (2020)

This study suggests that TPPU did not have rewarding effects in rodents. This would make sEH inhibitors potential therapeutic drugs without abuse potential for neuropathic pain.

Keyphrases

neuropathic pain
spinal cord
spinal cord injury
type diabetes
adipose tissue
risk assessment
intimate partner violence
climate change
drug induced