Methodical Manipulation of the TME in Ovarian Cancer.

Pamela Denisse Soberanis-Piña Amit M Oza

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2023)

The complex interplay between ovarian cancer (OC) cells and the tumor microenvironment (TME) modulates progression, with dynamic cellular interactions influenced by external modulators, including neoadjuvant chemotherapy (NACT). A recent article described the alterations within the TME following NACT, either with or without bevacizumab, in OC.

Keyphrases

neoadjuvant chemotherapy
locally advanced
induced apoptosis
lymph node
sentinel lymph node
cell cycle arrest
small molecule
rectal cancer
squamous cell carcinoma
radiation therapy
cell death
oxidative stress
endoplasmic reticulum stress
signaling pathway
cell proliferation
metastatic colorectal cancer