Protocol for long-term effect of pulmonary rehabilitation under nintedanib in idiopathic pulmonary fibrosis.
Osamu NishiyamaKensuke KataokaMasahiko AndoShinichi ArizonoAkira MorinoKoichi NishimuraTomoya OgawaAkira ShirakiFumiko WatanabeRyo KozuTakashi OguraYasuhiro KondohPublished in: ERJ open research (2021)
FITNESS is the first randomised controlled study to evaluate the long-term effects of pulmonary rehabilitation in IPF treated with nintedanib. This study will address the hypothesis that concomitant use of nintedanib contributes to the maintenance of long-term effects of pulmonary rehabilitation, thus leading to a comprehensive therapeutic approach of "nintedanib and pulmonary rehabilitation" in the antifibrotic era.