Hardy-Weinberg Equilibrium in different mitochondrial haplogroups of four genes associated with neuroprotection and neurodegeneration.

Sheida Mehrpour Camila Ronqui Rodrigues Renata Carmona Ferreira Marcelo Ribeiro da Silva Briones Acary de Souza Bulle de Oliveira

Published in: Arquivos de neuro-psiquiatria (2020)

HWE deviation of particular variants in relation to global populational HWE, could be, at least in part, associated with the differential susceptibility of specific populations and ethnicities to neurodegenerative diseases. Our data might contribute to the epidemiology and diagnostic/prognostic methods for neurodegenerative diseases.

Keyphrases

oxidative stress
electronic health record
copy number
molecular dynamics
brain injury
risk factors
molecular dynamics simulations
big data
cerebral ischemia
genetic diversity
dna methylation
data analysis
genome wide
blood brain barrier