Topologically-Interlocked Minicircles as Probes of DNA Topology and DNA-Protein Interactions.

Arivazhagan Rajendran Kirankumar Krishnamurthy Seojeong Park Eiji Nakata Youngjoo Kwon Takashi Morii

Published in: Chemistry (Weinheim an der Bergstrasse, Germany) (2022)

Invited for the cover of this issue are Prof. Takashi Morii and co-workers at Kyoto University and Ewha Womans University. The cover image depicts the graphical design and atomic force microscopic (AFM) images of the synthesized topologically-interlocked DNA catenane and rotaxanes inside a frame-shaped DNA origami. Read the full text of the article at 10.1002/chem.202200108.

Keyphrases

single molecule
circulating tumor
cell free
atomic force microscopy
deep learning
small molecule
photodynamic therapy
machine learning
mass spectrometry
fluorescence imaging