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Neurodevelopmental assessment of normocephalic children born to Zika virus exposed and unexposed pregnant people.

Jackeline AlgerMaría Luisa CafferataRaquel LópezLisa D WigginsAllison CallejasMario CastilloJenny FúnesFátima RicoDiana ValenciaDouglas VarelaZulma AlvarezMabel BerruetaHarry BockCarolina BustilloAlejandra CalderónAlvaro CigandaJorge García-AguilarKimberly GarcíaLuz GibbonsSuzanne M GilboaEmily W HarvilleGustavo HernándezWendy LópezIvette LorenzanaMarco T LuqueCarlos MaldonadoCynthia MooreCarlos OchoaLeda ParhamKarla PastranaAngel Paternina-CaicedoHeriberto RodríguezCandela StellaAyzsa F TannisDawn M WessonConcepción ZúnigaVan T TongPierre Buekens
Published in: Pediatric research (2023)
This study found no statistically significant differences in the neurodevelopment in normocephalic children with in utero Zika virus exposure compared to unexposed children, although the exposed group showed lower cognitive and language scores that persisted after adjustment by maternal age and education and after excluding children born preterm and low birth weight from the analysis. Children with prenatal Zika virus exposure, including those normocephalic and have no evidence of abnormalities at birth, should be monitored for neurodevelopmental delays. Follow-up is important to be able to detect developmental abnormalities that might not be detected earlier in life.
Keyphrases
  • zika virus
  • low birth weight
  • dengue virus
  • young adults
  • aedes aegypti
  • preterm infants
  • gestational age
  • preterm birth
  • human milk
  • physical activity
  • weight gain