Markers of neutrophil mediated inflammation associate with disturbed continuous electroencephalogram after out of hospital cardiac arrest.
Pirkka T PekkarinenFederico CarboneSilvia MinettiDavide RamoniGiuseppe RistagnoRoberto LatiniLauri WihersaariKaj BlennowHenrik ZetterbergJussi ToppilaPekka JakkulaMatti ReinikainenFabrizio MontecuccoMarkus B SkrifvarsPublished in: Acta anaesthesiologica Scandinavica (2022)
Elevated ICU admission levels of OPN and MPO predicted disturbances in cEEG during the subsequent 48 h after cardiac arrest. Thus, they may provide early information about the risk of secondary neurological damage. However, the studied inflammatory markers had little value for long-term prognostication compared to 48-hour NFL.