Adult CSF total protein upper reference limits should be age-partitioned and significantly higher than 0.45 g/L: a systematic review.
Thanh B NguyenDavid MoherJohn BrooksWei ChengHarald HegenFlorian DeisenhammerChristopher R McCuddenPierre R BourquePublished in: Journal of neurology (2019)
There is concordance in available literature to recommend increasing CSF total protein upper reference limits, and to consider implementing age-adjusted values above 0.60 g/L starting at age 50. This information merits worldwide dissemination, to reduce the risk of over-diagnosis.