Accurate image derived input function in [ 18 F]SynVesT-1 mouse studies using isoflurane and ketamine/xylazine anesthesia.

Alan MirandaDaniele BertoglioSteven StaelensJeroen Verhaeghe

Published in: EJNMMI physics (2023)

Image derived left ventricle blood activity calculated with NMF improves absolute activity quantification, and reduces the error in the kinetic modeling fit. These improvements are more pronounced in ketamine-xylazine than in isoflurane anesthetized mice.

Keyphrases

deep learning
pulmonary hypertension
pulmonary artery
mitral valve
high fat diet induced
coronary artery
congenital heart disease
left ventricular
chronic pain