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Exploration of cell type-specific somatic mutations in schizophrenia and the impact of maternal immune activation on the somatic mutation profile in the brain.

Jianbin DuYutaka NakachiYui MurataEmi KiyotaTadafumi KatoMiki BundoKazuya Iwamoto
Published in: Psychiatry and clinical neurosciences (2024)
Somatic mutations occurring at an earlier stage of brain cell differentiation toward neurons may be important for the cause of SZ. MIA may affect somatic mutation profiles in the brain.
Keyphrases
  • resting state
  • copy number
  • white matter
  • functional connectivity
  • cerebral ischemia
  • spinal cord
  • multiple sclerosis
  • pregnant women
  • spinal cord injury
  • birth weight