Release of cognitive and multimodal MRI data including real-world tasks and hippocampal subfield segmentations.
Ian A ClarkEleanor A MaguirePublished in: Scientific data (2023)
We share data from N = 217 healthy adults (mean age 29 years, range 20-41; 109 females, 108 males) who underwent extensive cognitive assessment and neuroimaging to examine the neural basis of individual differences, with a particular focus on a brain structure called the hippocampus. Cognitive data were collected using a wide array of questionnaires, naturalistic tests that examined imagination, autobiographical memory recall and spatial navigation, traditional laboratory-based tests such as recalling word pairs, and comprehensive characterisation of the strategies used to perform the cognitive tests. 3 Tesla MRI data were also acquired and include multi-parameter mapping to examine tissue microstructure, diffusion-weighted MRI, T2-weighted high-resolution partial volume structural MRI scans (with the masks of hippocampal subfields manually segmented from these scans), whole brain resting state functional MRI scans and partial volume high resolution resting state functional MRI scans. This rich dataset will be of value to cognitive and clinical neuroscientists researching individual differences, real-world cognition, brain-behaviour associations, hippocampal subfields and more. All data are freely available on Dryad.
Keyphrases
- contrast enhanced
- resting state
- diffusion weighted
- functional connectivity
- magnetic resonance imaging
- high resolution
- magnetic resonance
- computed tomography
- diffusion weighted imaging
- electronic health record
- white matter
- cerebral ischemia
- big data
- working memory
- multiple sclerosis
- machine learning
- mass spectrometry
- dual energy
- high throughput
- mild cognitive impairment
- blood brain barrier
- brain injury
- cognitive impairment
- single cell