Mapping hippocampal and thalamic atrophy in epilepsy: A 7-T magnetic resonance imaging study.
Alfredo LucasSofia MouchtarisAshley TranquilleNishant SinhaRyan GallagherMarissa MojenaJoel M SteinSandhitsu DasKathryn A DavisPublished in: Epilepsia (2024)
Leveraging 7-T MRI, we demonstrate widespread hippocampal and thalamic atrophy in epilepsy. Through unsupervised machine learning, we demonstrate patterns of volumetric atrophy that vary depending on disease subtype. Incorporating these atrophy patterns into clinical practice could help better stratify patients to surgical treatments and specific device implantation strategies.
Keyphrases
- machine learning
- magnetic resonance imaging
- clinical practice
- end stage renal disease
- deep brain stimulation
- contrast enhanced
- temporal lobe epilepsy
- ejection fraction
- chronic kidney disease
- newly diagnosed
- computed tomography
- prognostic factors
- artificial intelligence
- cerebral ischemia
- big data
- brain injury
- subarachnoid hemorrhage
- patient reported