Fu Fang Zhen Zhu Tiao Zhi Capsules Protect against Myocardial Ischemia by Inhibiting Cardiomyocyte Pyroptosis.

Xiaoqi Shao Bingying Huang Huiling Tan Ruonan Wang Xueying Huang Hongtao Diao Jiawen Cheng Mengxian Sun Dongwei Wang Kaili Wu Meiling Yan Xianglu Rong Yue Zhang Jiao Guo

Published in: Evidence-based complementary and alternative medicine : eCAM (2022)

FTZ could preserve cardiac function resulting from ischemic insult by inhibiting pyroptosis, which was partially reversed by NLRP3 overexpression, indicating that NLRP3 could be a potential target of FTZ in treating myocardial infarction.

Keyphrases

nlrp inflammasome
left ventricular
signaling pathway
heart failure
cell proliferation
transcription factor
angiotensin ii
ischemia reperfusion injury
human health
risk assessment
cerebral ischemia
brain injury
subarachnoid hemorrhage
blood brain barrier