Methodology for Using Real-World Data From Electronic Health Records to Assess Chemotherapy Administration in Women With Breast Cancer.
Jenna BhimaniKelli O'ConnellIsaac J ErgasMarilyn FoleyGrace B GallagherJennifer J GriggsNarre HeonTatjana KolevskaYuriy KotsurovskyyCandyce H KroenkeCecile A LaurentRaymond LiuKanichi G NakataSonia PersaudDonna R RiveraJanise M RohSara M TabatabaiEmily ValiceErin J Aiello BowlesElisa V BanderaLawrence H KushiElizabeth D KantorPublished in: JCO clinical cancer informatics (2024)
We describe the challenges and approaches to operationalize complex, real-world data to identify intended chemotherapy regimens in large, observational studies. This methodology can improve efficiency of use of large-scale clinical data in real-world populations, helping answer critical questions to improve care delivery and patient outcomes.