UPLC-MS based plasma metabolomics and lipidomics reveal alterations associated with IgG4-related disease.

Yiyi Gong Pan-Pan ZhangZheng LiuJieqiong LiHui LuYujie WangBintao QiuMu WangYunyun FeiHua ChenLinyi PengJing LiJiaxin ZhouQun ShiXuan ZhangMin ShenXiaofeng ZengFengchun ZhangWen Zhang

Published in: Rheumatology (Oxford, England) (2021)

IgG4-RD patients have a unique plasma metabolomic profile compared with healthy controls. Our study suggested that metabolomic profiling may provide important insights into pathophysiology and testable biomarkers for diagnosis of IgG4-RD.

Keyphrases

end stage renal disease
mass spectrometry
ejection fraction
chronic kidney disease
multiple sclerosis
single cell
genome wide
patient reported outcomes
high resolution
dna methylation