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The impact of an increased Fibrosis-4 index and the severity of hepatic steatosis on mortality in individuals living with diabetes.

Xiaoyan MaYixuan ZhuYee Hui YeoZhiwen FanXiaoming XuFajuan RuiWenjing NiQi GuXin TongShengxia YinXiaolong QiJunping ShiChao WuJie Li
Published in: Hepatology international (2024)
Liver fibrosis, as estimated by FIB-4, may serve as a more reliable prognostic indicator for individuals living with diabetes than hepatic steatosis. Individuals living with diabetes with FIB-4 ≥ 1.3 without moderate-severe steatosis had a significantly increased all-cause mortality risk. These findings highlight the importance of identifying and monitoring those individuals, as they may benefit from further evaluation and risk stratification.
Keyphrases
  • liver fibrosis
  • type diabetes
  • cardiovascular disease
  • glycemic control
  • early onset
  • high fat diet
  • risk factors
  • coronary artery disease
  • skeletal muscle
  • weight loss