Large is required for normal astrocyte migration and retinal vasculature development.

Min ZhouHerui WangHui RenRui JiangChi ZhangXiaohui WuGe-Zhi Xu

Published in: Cell & bioscience (2017)

Large is essential for ILM formation and retinal astrocyte migration. The novel Large mutant mouse can serve as a new PFV model to further dissect LARGE functions in ocular vasculature development.

Keyphrases

optical coherence tomography
diabetic retinopathy
optic nerve
wild type