Heritability and complex segregation analysis of diabetes mellitus in American Eskimo Dogs.

Stephen V CaiThomas R FamulaAnita M OberbauerRebecka S Hess

Published in: Journal of veterinary internal medicine (2019)

The estimated heritability of DM in AED is high but has low precision. Diabetes mellitus transmission in AED appears to follow a polygenic inheritance. Breeders could successfully implement a breeding program to decrease the incidence of DM in AED.

Keyphrases

glycemic control
type diabetes
risk factors
quality improvement
mitochondrial dna
metabolic syndrome
insulin resistance
dna methylation
adipose tissue
copy number
genome wide