MiR-192/NKRF axis confers lung cancer cell chemoresistance to cisplatin via the NF-κB pathway.

Yang LiLingling ZuHeng WuFang ZhangYa-Guang FanHongli PanXinxin DuFengjie GuoQinghua Zhou

Published in: Thoracic cancer (2021)

MiR-192 plays a crucial role in cisplatin-resistance of lung cancer cells. Thus, MiR-192 may represent a therapeutic target for overcoming resistance to cisplatin-based chemotherapy in lung cancer.

Keyphrases

cell proliferation
long non coding rna
long noncoding rna
signaling pathway
oxidative stress
pi k akt
nuclear factor
immune response
radiation therapy
inflammatory response
toll like receptor
rectal cancer
chemotherapy induced