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Analytical validation of quantitative SARS-CoV-2 subgenomic and viral load laboratory developed tests conducted on the Panther Fusion® (Hologic) with preliminary application to clinical samples.

Ines Elakhal-NaouarHolly R HackEdgar MoradelAmie JarraHannah L GroveRani M IsmaelSteven PadillaDante ColemanJason OuelletteJanice DardenCasey StormeKristina K PeachmanTara L HallMark E HuhtanenPaul T ScottShilpa HakreLinda L JagodzinskiSheila A Peel
Published in: PloS one (2023)
The LDT-Quant sgRNA and LDT-Quant VLCoV demonstrated good analytical performance. These assays could be further investigated as alternative monitoring assays for viral replication; and thus, medical management in clinical settings which could inform isolation/quarantine requirements.
Keyphrases
  • sars cov
  • high throughput
  • healthcare
  • liquid chromatography
  • atomic force microscopy
  • high speed