Validation of a multiplex flow immunoassay for detection of IgG antibodies against SARS-CoV-2 in dried blood spots.

Coleman T TurgeonKaren A SandersPiero RinaldoDane GrangerHeather HilgartDietrich MaternElitza S Theel

Published in: PloS one (2021)

Use of DBS for detection of antibodies against SARS-CoV-2 provides comparable results to those obtained using serum. DBS concordance was improved with multivariate pattern recognition software (CLIR). We demonstrate that DBS are a reliable specimen type for SARS-CoV-2 antibody detection using the modified Luminex xMAP assay.

Keyphrases

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loop mediated isothermal amplification
data analysis
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water quality