Coexistence of Eph receptor B1 and ephrin B2 in port-wine stain endothelial progenitor cells contributes to clinicopathological vasculature dilatation.

Wenbin TanJ WangF ZhouL GaoR YinH LiuA SukanthanagG WangM C MihmD-B ChenJ S Nelson

Published in: The British journal of dermatology (2017)

PWS ECs are differentiation-impaired, late-stage endothelial progenitor cells with a specific phenotype of CD133+ /CD166+ /EphB1+ /EfnB2+ , which form immature venule-like pathoanatomical vasculatures. The disruption of normal EC-EC interactions by coexistence of EphB1 and EfnB2 contributes to progressive dilatation of PWS vasculatures.

Keyphrases

endothelial cells
multiple sclerosis
binding protein
laparoscopic surgery
minimally invasive