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Better characterization of vinflunine pharmacokinetics variability and exposure/toxicity relationship to improve its use: Analyses from 18 trials.

Antonin SchmittLaurent NguyenGrégoire ZorzaPierre FerréAurélie Pétain
Published in: British journal of clinical pharmacology (2018)
We propose for the first time a global comprehensive clinical pharmacological analysis for intravenous vinflunine that may help drive dose adjustment.
Keyphrases
  • oxidative stress
  • high dose