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Depressive symptoms in patients after primary and secondary prophylactic ICD implantation.

Caroline EnsslinJan BergJulia Hermes-LauferLukas S KellerDavid NiederseerAju PazhenkottilRoland von KänelChristian M Schmied
Published in: Clinical research in cardiology : official journal of the German Cardiac Society (2021)
Overall, depressive symptoms were common in ICD patients, with 20.3% of the patients showing clinically relevant depression (12.4% mild depressive symptoms, 6.0% moderate, 1.9% severe). Moderate to severe depressive symptoms seem to be more likely in patients with secondary prophylactic indication of the ICD as compared to a group of patients with primary prophylactic implantation. Patients that received more than 5 ICD shocks since implantation reveal more depressive symptoms than those with less events. Mean BDI Score in total (n = 315) was at 8.44 ± 7.56 without a statistically significant difference between the primary (M = 8.04 ± 7.10, n = 153) and secondary (M = 8.81 ± 7.98, n = 162) preventive group (p value = 0.362), even after adjustment for various clinical characteristics. ICD patients should therefore be well supported and advised concerning the psychological impact of their device and particular aspects of daily life concerns (e.g. physical activity), with a special focus on patients, who have received multiple shocks.
Keyphrases
  • depressive symptoms
  • end stage renal disease
  • chronic kidney disease
  • ejection fraction
  • newly diagnosed
  • physical activity
  • peritoneal dialysis
  • prognostic factors
  • gene expression
  • genome wide