Extrusion-based systems for topical and transdermal drug delivery.
Ana Luiza LimaIdejan P GrossLívia Lira de Sá-BarretoTais GratieriGuilherme Martins GelfusoMarcilio Cunha-FilhoPublished in: Expert opinion on drug delivery (2023)
A wide variety of pharmaceutical products can be obtained using HME and FDM 3D printing, including new dosage forms designed for a perfect anatomical fit. Despite the limitations of pharmaceutical products produced with HME and FDM 3D printing regarding thermal stability and available excipients, the advantages in industrial adaptability and improved bioavailability allied with patient-match devices certainly deserve full attention and investment.