Maraviroc Population Pharmacokinetics Within the First 6 Weeks of Life.
Marlon LiyanageMina NikanjamLynn McFadyenManoli VourvahisLuise RoggJohn MoyeEllen G ChadwickPatrick Jean-PhilippeMark MirochnickKyle WhitsonSarah BradfordEdmund V CapparelliBrookie M BestPublished in: The Pediatric infectious disease journal (2022)
While maraviroc apparent clearance is decreased in the first few days of life, the current FDA-approved maraviroc weight band dosing provides maraviroc exposures for neonates in the first 6 weeks of life, which were consistent with adult maraviroc exposure range. Maraviroc provides another antiretroviral treatment option for very young infants.