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Maraviroc Population Pharmacokinetics Within the First 6 Weeks of Life.

Marlon LiyanageMina NikanjamLynn McFadyenManoli VourvahisLuise RoggJohn MoyeEllen G ChadwickPatrick Jean-PhilippeMark MirochnickKyle WhitsonSarah BradfordEdmund V CapparelliBrookie M Best
Published in: The Pediatric infectious disease journal (2022)
While maraviroc apparent clearance is decreased in the first few days of life, the current FDA-approved maraviroc weight band dosing provides maraviroc exposures for neonates in the first 6 weeks of life, which were consistent with adult maraviroc exposure range. Maraviroc provides another antiretroviral treatment option for very young infants.
Keyphrases
  • body mass index
  • physical activity
  • human immunodeficiency virus
  • hiv infected
  • magnetic resonance imaging
  • hiv aids
  • computed tomography
  • magnetic resonance
  • hiv positive
  • combination therapy
  • antiretroviral therapy