Possible Role of CD11a in Primary Immune Thrombocytopenia Patients on Immunosuppressive Therapy.

Muhamad R Abdel HameedHowiada A NafadyMona Ibrahim MostafaDouaa SayedAhmad A Obiedallah

Published in: Journal of blood medicine (2021)

CD11a had possible role in the pathogenesis of ITP. Immunosuppressive therapy in ITP did not affect the level of CD11a expression on T and B lymphocytes. Levels of CD11a do not reflect the severity of ITP neither platelet count nor bleeding score. Increased MFI of CD11a in CD3+T lymphocytes of ITP patients may cause resistance to immunosuppressive therapy.

Keyphrases

end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
nk cells
prognostic factors
peritoneal dialysis
patient reported outcomes
bone marrow
cell therapy