Association Between Trimethylamine N-oxide and Adverse Kidney Outcomes and Overall Mortality in Type 2 Diabetes Mellitus.

Ping-Shaou Yu Ping-Hsun Wu Wei-Wen Hung Ming-Yen LinYen-Yi ZhenWei-Chun Hung Jer-Ming Chang Jong-Rung Tsai Yi-Wen Chiu Shang-Jyh Hwang Yi-Chun Tsai

Published in: The Journal of clinical endocrinology and metabolism (2024)

Patients with T2D with elevated circulating TMAO levels are at higher risk of doubling serum creatinine, progressing to ESKD, and mortality. TMAO is a potential biomarker for kidney function progression and mortality in patients with T2D.

Keyphrases

cardiovascular events
risk factors
emergency department
cardiovascular disease
coronary artery disease
skeletal muscle
metabolic syndrome
insulin resistance
weight loss