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Performance evaluation of the FastIC readout ASIC with emphasis on Cherenkov emission in TOF-PET.

Markus PillerAntonio M CastillaGiulia TerragniJerome AlozyEtiennette AuffrayRafael BallabrigaMichael CampbellBernd DeutschmannDavid GasconAlberto GolaStefano MerziAlicja Michalowska-ForsythMichele PennaSergio Gómez FernándezNicolaus Kratochwil
Published in: Physics in medicine and biology (2024)
Objective. The efficient usage of prompt photons like Cherenkov emission is of great interest for the design of the next generation, cost-effective, and ultra-high-sensitivity time-of-flight positron emission tomography (TOF-PET) scanners. With custom, high power consuming, readout electronics and fast digitization the prospect of sub-300 ps FWHM with PET-sized BGO crystals have been shown. However, these results are not scalable to a full system consisting of thousands of detector elements. Approach. To pave the way toward a full TOF-PET scanner, we examine the performance of the FastIC ASIC with Cherenkov-emitting scintillators (BGO), together with one of the most recent SiPM detector developments based on metal trenching from FBK. The FastIC is a highly configurable ASIC with 8 input channels, a power consumption of 12 mW ch -1 and excellent linearity on the energy measurement. To put the timing performance of the FastIC into perspective, comparison measurements with high-power consuming readout electronics are performed. Main results. We achieve a best CTR FWHM of 330 ps for 2 × 2 × 3 mm 3 and 490 ps for 2 × 2 × 20 mm 3 BGO crystals with the FastIC. In addition, using 20 mm long LSO:Ce:Ca crystals, CTR values of 129 ps FWHM have been measured with the FastIC, only slightly worse to the state-of-the-art of 95 ps obtained with discrete HF electronics. Significance. For the first time, the timing capability of BGO with a scalable ASIC has been evaluated. The findings underscore the potential of the FastIC ASIC in the development of cost-effective TOF-PET scanners with excellent timing characteristics.
Keyphrases
  • positron emission tomography
  • computed tomography
  • pet ct
  • mass spectrometry
  • pet imaging
  • ms ms
  • image quality
  • room temperature
  • magnetic resonance imaging
  • heart failure
  • high resolution
  • energy transfer