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Risk of Recurrence in Patients with an Unprovoked Tonic-Clonic Seizure and Generalized Epileptiform Discharges on EEG.

Najo JomaaWassim NasreddineGhassan HmeimessShawkat BeainiAyman BeydounMostafa HotaitJaafar WazneAhmad Beydoun
Published in: Epilepsia (2023)
Patients with a first unprovoked GTC seizure and evidence of GSWD on EEG have a high risk of recurrence if left untreated. Valproate is the most efficacious ASD for preventing recurrence in this population. A sizeable proportion of patients can be successfully tapered off medication after a period of seizure freedom. This study provides valuable information for guiding treatment decisions in this patient population.
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