Advanced lipoprotein profile disturbances in type 1 diabetes mellitus: a focus on LDL particles.

Antonio J AmorEsmeralda CastelblancoMarta HernándezMarga GimenezMinerva Granado-CasasJesús BlancoBerta SoldevilaEnric EsmatjesIgnacio CongetNuria AlonsoEmilio OrtegaEsmeralda Castelblanco

Published in: Cardiovascular diabetology (2020)

Overall, T1DM participants showed a more favourable conventional and NMR-lipid profile than controls. However, the NMR-assessment identified several lipoprotein derangements in LDL-particles among the T1DM population (higher discrepancies in NMR-LDL-particles vs. conventional LDL-cholesterol; a worse profile in T1DM women) that were overlooked in the conventional analysis. Further studies are needed to elucidate their role in the development of CVD in this population.

Keyphrases

low density lipoprotein
magnetic resonance
high resolution
solid state
polycystic ovary syndrome
glycemic control
pregnant women