Prenatal diagnosis of middle interhemispheric variant of holoprosencephaly: review of literature and prenatal case series.

Ine Tavano Bart De Keersmaecker Michael Aertsen Luc de Catte

Published in: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians (2021)

MIH variant of HPE is detectable from the early second trimester and should be considered in the differential diagnosis when the cavum septi pellucidi (CSP) is absent. Genetic analysis and autopsy should be conducted to investigate this more recent and rare variant.

Keyphrases

pregnant women