Soluble CD163 and mannose receptor associate with chronic hepatitis B activity and fibrosis and decline with treatment.

Tea Lund LaursenGrace Lai-Hung WongKonstantin KazankovThomas SandahlHolger Jon MøllerStephen Hamilton-DutoitJacob GeorgeHenry Lik-Yuen ChanHenning Grønbaek

Published in: Journal of gastroenterology and hepatology (2018)

The macrophage activation markers sCD163 and sMR were associated with activity and fibrosis in liver biopsies from CHB patients. Both serum markers decreased with antiviral treatment, along with decreased hepatic CD163 expression.

Keyphrases

end stage renal disease
ejection fraction
prognostic factors
binding protein
liver fibrosis