Neurofilament light chain is elevated in patients with newly diagnosed idiopathic intracranial hypertension: A prospective study.
Katrine SvartJohanne Juhl KorsbaekRigmor Højland JensenTina ParknerCindy Søndersø KnudsenSteen Gregers HasselbalchSnorre Malm HagenElisabeth Arnberg WibroeLaleh Dehghani MolanderDagmar BeierPublished in: Cephalalgia : an international journal of headache (2024)
cNfL, pNfL and total-tau/Aβ-42 were elevated in new-onset idiopathic intracranial hypertension. cNfL was associated with severity of papilledema and visual field defects at diagnosis. This indicates early axonal damage. Neurofilament light chain is a candidate biomarker for disease severity.