Ligand-Induced Red-Emitting Copper Nanoclusters for Selective Fluorescence Determination of Aluminum Ions.
Lili YuanQian ZhangLina YuYanan WuCaiyun WangCongying ShaoShun LuPublished in: Inorganic chemistry (2024)
Monitoring levels of excessive aluminum ions (Al 3+ ) is crucial as it can harm the immune system, reduce enzyme activity, cause cell death, and damage environmental and biological systems. Developing a fast and efficient Al 3+ ion determination method is the key to addressing this issue. In this work, red-emitting fluorescent copper nanoclusters (CuNCs) were synthesized using N -acetyl-l-cysteine (NAC) as a ligand and CuCl 2 ·2H 2 O through a facile procedure. The NAC-CuNCs exhibited a large Stokes shift and displayed remarkable luminescence properties. A method for detecting Al 3+ through a fluorescence probe was proposed. Its fluorescence mechanism was also explored. The probe showed rapid responsiveness (within 1 min) to Al 3+ ion determination. The detection limit for Al 3+ was found to be 19.7 nM, which is significantly lower than the WHO's value and most reports, with a linear range of 0-52.9 μM. The determination of Al 3+ concentrations in actual water using the fluorescence probe yielded satisfactory outcomes. Moreover, the visual detection of Al 3+ ions was also achieved through a smartphone, which can enhance its fast and practical detection.
Keyphrases
- quantum dots
- energy transfer
- sensitive detection
- fluorescent probe
- loop mediated isothermal amplification
- label free
- cell death
- single molecule
- solid phase extraction
- transcription factor
- oxidative stress
- risk assessment
- emergency department
- photodynamic therapy
- body mass index
- physical activity
- adipose tissue
- metabolic syndrome
- insulin resistance
- water soluble
- weight loss
- climate change
- human health