Association of polymorphism in leptin receptor gene with susceptibility of adolescent idiopathic scoliosis.

Antonio Eulalio Pedrosa Araujo JuniorGustavo Borges Laurindo de AzevedoLuis Antonio Medeiros MoliternoRenato Henriques TavaresJessica Vilarinho CardosoGiuliana Rodrigues de SouzaJoão Antonio Matheus GuimarãesHelton Luiz Aparecido DefinoJamila Alessandra Perini Machado

Published in: European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society (2023)

The LEPR rs2767485 was associated with the genetic susceptibility of AIS and LEP rs2167270 with low BMI. These data can contribute to the identification of genetic biomarkers to improve the diagnosis and treatment.

Keyphrases

genome wide
copy number
body mass index
electronic health record
gene expression
data analysis