Unexpectedly High Prevalence of Low Alpha-Galactosidase A Enzyme Activity in Patients with Focal Segmental Glomerulosclerosis.

Nuri Baris Hasbal Feyza Bayrakdar Caglayan Tamer Sakaci Elbis Ahbap Yener Koc Mustafa Sevinc Zuhal Atan Ucar Abdulkadir Unsal Taner Basturk

Published in: Clinics (Sao Paulo, Brazil) (2020)

We found that αGAL activity in patients with FSGS is lower than that in patients undergoing HD. The low enzyme activity in patients with FSGS may be explained by considering the similar pathogenesis of FSGS and FD, which may also lead to sphingolipid deposition and podocyte injury.

Keyphrases

patients undergoing
endothelial cells