A rapid assessment of wastewater for genomic surveillance of SARS-CoV-2 variants at sewershed scale in Louisville, KY.

J L FuquaE C RouchkaS WaigelK SokoloskiD ChungW ZachariasM ZhangJ CharikerD TalleyI SantistebanDarren P MartinS MoyerRochelle H HolmR A YeagerT SmithA Bhatnagar

Published in: medRxiv : the preprint server for health sciences (2021)

In this communication, we report on the genomic surveillance of SARS-CoV-2 using wastewater samples in Jefferson County, KY. In February 2021, we analyzed seven wastewater samples for SARS-CoV-2 genomic surveillance. Variants observed in smaller catchment areas, such as neighborhood manhole locations, were not necessarily consistent when compared to associated variant results in downstream treatment plants, suggesting catchment size or population could impact the ability to detect diversity.

Keyphrases

sars cov
copy number
public health
wastewater treatment
respiratory syndrome coronavirus
anaerobic digestion
genome wide
dna methylation
physical activity