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Systematic review of efficacy and meta-analysis of safety of ranibizumab biosimilars relative to reference ranibizumab anti-VEGF therapy for nAMD treatment.

Amin HatamnejadRohan DadakSamantha OrrCharles WykoffNetan Choudhry
Published in: BMJ open ophthalmology (2023)
This systematic review of four RCTs demonstrated no significant difference in visual outcomes, retinal thickness outcomes, as well as meta-analysis of adverse events between biosimilar and reference ranibizumab therapies for nAMD treatment.
Keyphrases
  • systematic review
  • diabetic retinopathy
  • meta analyses
  • optical coherence tomography
  • endothelial cells
  • vascular endothelial growth factor
  • adipose tissue
  • glycemic control