Antibody Responses to SARS-CoV-2 after Infection or Vaccination in Children and Young Adults with Inflammatory Bowel Disease.
Joelynn DaileyLina KozhayaMikail DoganDena HopkinsBlaine LapinKatherine HerbstMichael BrimacombeKristen GrandonicoFaith KarabacakJohn SchreiberBruce Tsan-Liang LiangJuan C SalazarDerya UnutmazJeffrey S HyamsPublished in: medRxiv : the preprint server for health sciences (2021)
Our study showed a low and poorly durable SARS-CoV-2 S-RBD neutralizing IgG response to natural infection in IBD patients receiving biologics potentially putting them at risk of reinfection. However, they also had a robust response to immunization that is likely protective.