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TP53 Sequencing and p53 Immunohistochemistry Predict Outcomes When Bevacizumab Is Added to Frontline Chemotherapy in Endometrial Cancer: An NRG Oncology/Gynecologic Oncology Group Study.

Kristina W W ThielEric J DevorVirginia L FiliaciDavid G MutchKatherine MoxleyAngeles A SecordKrishnansu S TewariMegan E McDonaldCara A MathewsCasey CosgroveSummer DewdneyCarol AghajanianMegan I SamuelsonHeather A LankesRobert A SoslowKimberly Kay Leslie
Published in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2022)
identifies a specific, high-risk tumor genotype/phenotype for which bevacizumab is particularly beneficial in improving outcomes when combined with chemotherapy.
Keyphrases
  • endometrial cancer
  • palliative care
  • locally advanced
  • genome wide
  • adipose tissue
  • radiation therapy
  • weight loss
  • chemotherapy induced