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miR-101-3p improves neuronal morphology and attenuates neuronal apoptosis in ischemic stroke in young mice by downregulating HDAC9.

Mengru ZhangJianjun WangJinfang LiFanxin KongSongjun Lin
Published in: Translational neuroscience (2023)
Activation of miR-101-3p can protect against IS in young mice, and its mechanism is relevant to the inhibition of HDAC9. Therefore, miR-101-3p and HDAC9 might be the latent targets for IS therapy.
Keyphrases
  • histone deacetylase
  • high fat diet induced
  • middle aged
  • oxidative stress
  • cerebral ischemia
  • endoplasmic reticulum stress
  • cell death
  • stem cells
  • cell cycle arrest
  • wild type
  • bone marrow