CCNE1 Is a Putative Therapeutic Target for ARID1A-Mutated Ovarian Clear Cell Carcinoma.

Naoki KawaharaYuki YamadaHiroshi Kobayashi

Published in: International journal of molecular sciences (2021)

This study showed for the first time that CCNE1 is a synthetic lethal target gene to ARID1A-mutated OCCC. Targeting this gene may represent a putative, novel, anticancer strategy in OCCC treatment.

Keyphrases

copy number
genome wide
genome wide identification
combination therapy
genome wide analysis
smoking cessation