Clinical relevance of the in situ assay for HBV DNA: a cross-sectional study in patients with chronic hepatitis B.
Danping LiuTong XuBisheng ShiWei LuYe ZhengYanling FengZhenghong YuanXiao-Nan ZhangZhanqing ZhangPublished in: Journal of clinical pathology (2020)
The ISH assay for HBV DNA reflects the vigour of intrahepatic viral replication. It is complementary to the routine IHC assay for viral antigens and also related to the histopathological progression of liver diseases. The application of the HBV DNA ISH assay may help a better evaluation of virological and pathological condition of patients with CHB.