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Serum Metabolites Relate to Mucosal and Transmural Inflammation in Pediatric Crohn Disease.

Ricardo G SuarezNamitha GuruprasadGanesh TataZhengxiao ZhangGili FochtDaniel McClementVíctor Manuel Navas-LópezSibylle KoletzkoAnne M GriffithsOren LedderLissy de RidderDavid WishartBen NicholsKonstantinos GerasimidisDan TurnerEytan Wine
Published in: Journal of Crohn's & colitis (2024)
We extend on recent studies, observing differences in serum metabolite between healthy controls and Crohn disease patients, and suggest various associations of serum metabolites with transmural and mucosal inflammation. These metabolites could improve the understanding of pCD pathogenesis and assess disease severity.
Keyphrases
  • ms ms
  • end stage renal disease
  • oxidative stress
  • newly diagnosed
  • chronic kidney disease
  • ejection fraction
  • peritoneal dialysis
  • ulcerative colitis
  • patient reported outcomes
  • case control