The sensor kinase BfmS controls production of outer membrane vesicles in Acinetobacter baumannii.
Se Yeon KimMi Hyun KimSeung Il KimJoo Hee SonShukho KimYoo Chul LeeMinsang ShinMan Hwan OhJe-Chul LeePublished in: BMC microbiology (2019)
The present study demonstrates that BfmS controls production of OMVs in A. baumannii. Moreover, BfmS negatively regulates antimicrobial resistance of A. baumannii and OMV-mediated host cell cytotoxicity. Our results indicate that BfmS negatively controls the pathogenic traits of A. baumannii via cell envelope structures and OMV production.